In today’s fast-paced world, stress has become an almost constant companion. Whether it’s the demands of work, the chaos of daily life, or the overwhelming influx of information, it’s easy to feel overwhelmed. Fortunately, there are natural remedies that can help us manage stress, and one of these is Kanna, also known as Sceletium tortuosum.

What is Kanna?

Kanna is a succulent plant native to South Africa, where it has been used for centuries by indigenous peoples for its calming effects. Traditionally, the leaves of the plant were chewed to help reduce anxiety and improve mood during stressful situations. This ancient practice highlights Kanna’s potential in helping us navigate the stressors of modern life.

How Does Kanna Work?

Kanna’s stress-relieving properties are attributed to its active compounds, particularly a group of alkaloids known as mesembrine alkaloids. These compounds have two primary actions in the body that contribute to their anxiolytic (anti-anxiety) effects:

  1. Serotonin Reuptake Inhibition: Kanna acts as a serotonin reuptake inhibitor (SRI). Serotonin is a neurotransmitter that plays a key role in mood regulation. By inhibiting its reuptake, Kanna allows serotonin to remain in the synaptic gap longer, enhancing its mood-boosting effects and reducing feelings of anxiety.
  2. Phosphodiesterase 4 (PDE4) Inhibition: PDE4 is an enzyme involved in the breakdown of certain signaling molecules within nerve cells. Overactivity of PDE4 can contribute to cognitive decline, increased stress, and mood disturbances. By inhibiting PDE4, Kanna helps maintain better cognitive function, reduces stress, and promotes a more positive mood.

Benefits and Usage

Kanna offers a gentle yet effective way to manage stress. It doesn’t provide an overwhelming sense of euphoria or sedation, but rather helps to smooth the edges of everyday anxiety. Here are some practical applications:

  • Stress Reduction: Incorporating Kanna into your daily routine can help make stressful tasks more manageable and reduce overall anxiety.
  • Enhanced Focus: Kanna is often found in nootropic supplements due to its ability to improve focus and cognitive function.
  • Pre-workout Boost: When used as part of a pre-workout supplement, Kanna can help you channel energy more effectively, enhancing performance without causing jitters.

Safety and Dosage

Kanna is generally well-tolerated, with few reported side effects. Most people can take up to 500mg without significant issues, though some may experience mild gastrointestinal discomfort at higher doses. As with any supplement, it’s important to start with a lower dose to see how your body responds.


As we continue to face increasing levels of stress in our daily lives, finding natural ways to cope is essential. Kanna, with its rich history and scientifically-backed benefits, offers a promising solution. Remember to approach its use responsibly, starting with small doses and observing how it affects you. With Kanna, you might just find that the challenges of modern life become a little easier to handle.